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Serene Science 5-HTP
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Serene Science 5-HTP

Balanced Mood

from Source Naturals
Retail $23.50
 you save 30%
Size: 60 Capsules - 100 mg
Item: 5500
Weight: 0.11 lbs
Points: 82
5-HTP (L-5-Hydroxytryptophan) is an intermediate in the natural conversion of the essential amino acid tryptophan, to serotonin, which is a neurotransmitter. Clinical studies have shown that 5-HTP increases the amount and availability of serotonin produced by the body. Support your healthy moods, eating habits, and sleep cycles with the science of Source Naturals 5-HTP today.

  • Description
  • Supplement Facts & Suggested Use
  • Reviews

5-HTP for Balanced Mood

  • HN-all-natural
  • MG-gluten-free
  • ND-dairy-free
  • OS-soy-free
  • PY-yeast-free

5-HTP (L-5-Hydroxytryptophan) is an intermediate in the natural conversion of the essential amino acid tryptophan, to serotonin, which is a neurotransmitter. Clinical studies have shown that 5-HTP increases the amount and availability of serotonin produced by the body. It may support healthy moods, eating habits, and sleep cycles.†

Source Naturals 5-HTP is naturally derived from the seeds of the African plant Griffonia simplicifolia.

How 5-HTP Works

5-HTP may help support the body’s balanced production of two important sleep regulating hormones—serotonin, and melatonin. Eventually, the serotonin in your body is converted into melatonin, the hormone that helps regulate healthy 24-hour sleep cycles known as circadian rhythms.

Aging, hormone imbalance, and various forms of physical or emotional stress can decrease melatonin levels and disrupt sleep cycles. Fortunately, that balance can be recouped. When 5-HTP increases serotonin production, melatonin production is also increased, which helps the body regain a healthy circadian rhythm.† However, you need adequate serotonin levels to maintain this balance.

Increased brain serotonin levels may produce positive effects on:
  • Emotional well-being†
  • Appetite regulation†
  • Melatonin production†
  • Maintaining a healthy sleep cycle†

5-HTP The Science of Sleep

Sleep is especially important in today's world. It's the time when the body repairs, rebuilds, and replenishes the tissues and compounds that have been damaged or depleted by the daily demands of life. But when there is too much stress, imbalances occur that can keep you from getting enough sleep.

5-HTP may help promote healthy sleep cycles. It's created when the tryptophan in the body is converted into serotonin. 5-HTP can cross the blood-brain barrier and is associated with increasing active serotonin levels as well as serotonin production.†

5-HTP may also be beneficial for:

  • improvements in mood or feelings of anxiousness
  • support for occasional sleeplessness
  • appetite regulation as part of a healthy weight management plan


Individuals taking the antidepressant medications known as selective serotonin reuptake inhibitors (SSRIs) (such as fluoxetine, paroxetine, sertraline, and citalopram) and monoamine oxidase inhibitors (MAOIs) (such as phenelzine, isocarboxazid, selegiline, and tranylcypromine) should not use 5-HTP, as it enhances the action of these drugs and may increase the risk for developing a dangerous condition known as "serotonin syndrome." Serotonin syndrome is characterized by mental status changes, rigidity, hot flashes, rapidly fluctuating blood pressure and heart rate, and possibly coma.

Similarly, other drugs for depression that interfere with the uptake of the neurotransmitter serotonin, namely trazodone and venlafaxine, may also lead to serotonin syndrome when used along with 5-HTP. If you are currently taking any of the above prescription medications, you should not use 5-HTP without first talking to your healthcare provider.

5-HTP may cause mild gastrointestinal disturbances including nausea, heartburn, flatulence, feelings of fullness, and rumbling sensations in some people. Pregnant or nursing women and individuals with high blood pressure or diabetes should consult a healthcare practitioner before taking 5-HTP.

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  1. Birdsall, T. (1998). 5-Hydroxytryptophan: a clinically effective serotonin precursor. Alternative Medicine Review: a Journal of Clinical Therapeutic 3(4): 271-280.
  2. Magnussen, T., et al. (1981). Plasma accumulation and metabolism of orally administered single dose L-5-Hydroxytryptophan in man. Basic & Clinical Pharmacology & Toxicology (BCPT) 49:184-189.
  3. Magnussen, T., et al. (1980). Bioavailability and related pharmacokinetics in man of orally administered L-5-hydroxytryptophan in steady state. Basic & Clinical Pharmacology & Toxicology (BCPT) 46: 257-262.

Supplement Facts - Serene Science 5-HTP

Capsules per Container: 60 Capsules, 100 mg
Serving Size: Two (2) Capsules
Servings per Container: 60

Supplement Facts for 100 mg Capsule

5-HTP (from Griffonia simplicifolia), 100 mg (†)

† Daily Value not established.

Other Ingredients: microcrystalline cellulose, gelatin (capsule), silica, and magnesium stearate.

HYPOALLERGENIC: Contains no yeast, dairy, egg, gluten, corn, soy, or wheat. Contains no sugar, starch, salt, preservatives, artificial colors, flavor, or fragrance.

Suggested Use: 1 or 2 capsules once or twice daily with meals, or as directed by your healthcare professional

Warning: Not for use by children, or pregnant or lactating women. If you are taking antidepressants, SSRIs, MAOIs, sedatives, painkillers, or other drugs, or if you have any medical condition, consult your physician before taking 5-HTP. In some people, temporary nausea, diarrhea, or abdominal discomfort may occur. If these symptoms occur, lower the dose, or spread the dose throughout the day. Discontinue use if any of these symptoms persist for more than three days. May cause drowsiness; do not drive or operate heavy machinery until you know how 5-HTP affects you.

Do not use if either tamper-evident seal is broken or missing. Keep out of the reach of children.

Manufactured by Source Naturals.

† These statements have not been evaluated by the U.S. Food and Drug Administration (FDA) or This product is not intended to diagnose, treat, cure or prevent any disease. The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging. You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. You should consult with a health care professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem, or are pregnant. When you receive an item, carefully read all labels, warnings, and directions before use. Actual product packaging and materials may contain more and/or different information than shown on this website.

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