Collagen Types 1, 2, & 3 – Knowing the Important Differences
Collagen is Protein
Perhaps you’ve used collagen supplements or taken a form of gelatin to help improve the health of your hair, skin or nails. But do you know there are different collagen types and which types are better taken together or apart from each other? Did you know that aside from water, collagen is the most plentiful substance in our bodies and is a building block for skin, tendons, and bones?
Collagen types contain different proteins which serve separate purposes within the body. Types 1 & 3 can be taken together and may support skin, muscles, bone health, and hair and nail growth and maintenance*. Collagen Type 2 protein makes up the fluids and function in the cartilage and joints. Type 2 collagen supplements should be taken separately from Types 1 & 3 to ensure adequate absorption*.
There are 19 amino acids (proteins) found in Collagen Types 1 & 3 – each essential to functions and maintenance within skin, muscles, and bones. These types are produced by fibroblasts (cells in connective tissues) and osteoblasts (cells that make bones).
Over 90 percent of collagen in the body is comprised of Type 1 & 3 Collagen. Proteins in these types include glycine, proline, alanine, and hydroxyproline.
- Glycine – the amino acid found at the highest levels in collagen, requires more serine than our bodies can naturally produce. Studies suggest the need for glycine supplementation to achieve ideal metabolic processes 1.
- Proline – a non-essential amino acid synthesized from glycine and important in function of joints and tendons 2
- Hydroxyproline – amino acid that plays an essential role in the stability of collagen 3
- Alanine – amino acid used in the biosynthesis of proteins 4
Collagen Type 2 is produced by chondrocytes (the non-cellular matrix of cartilage) – a liquid-like filling within the cartilage.
Why supplement with collagen if it already naturally occurs in the body?
Over time, the ideal levels of collagen our bodies naturally produce begin to wane. Collagen fibers break down or no longer regenerate, and lead to a “deflation” effect on the surface of the skin.
The diminishing effects of reduced collagen Type 2 are less obvious and often go unnoticed or are considered “normal” for the aging process.
Research indicates that by the age of 40, the body’s ability to produce collagen decreases by 25%. By age 60, it has decreased by over 50%.*
Despite being made up of non-essential amino acids, the supply of ideal levels of naturally occurring collagen cannot meet the demand.
Though it is possible to obtain extra collagen through diet (consuming animal products such as gelatinous meats, the cartilage on bones such as chicken drumsticks, and skin from poultry 5), some may find it unappealing or difficult to eat enough to support their body’s requirements.
Collagen Types 1 & 3 for Hair, Skin, Nails, and Bones
Suggested use to take with juice or Vitamin C supplement in the morning. Take separately from Type 2 Collagen.
Collagen Types 1 & 3 may:
- minimize fine lines and wrinkles*
- improve elasticity*
- support the bone matrix (36% of bone is made up of collagen Type 1 and 3)*
- correct weak or damaged nail beds*
- thicken fine hair, slows hair loss*
- improve circulation*
- promote glycine production which builds leans muscle and helps burn fat during sleep*
Supplementing with collagen may also, “increase skin hydration by 28%, decrease micro-furrows by 26%, and increase skin suppleness by 19%”* – NeoCell Products and Tips
Collagen Type 2 for Joint and Cartilage Support
Suggested use to take at bedtime on an empty stomach. To improve effectiveness, do not take in conjunction with Type 1 & 3.
Collagen Type 2:
- makes up 50-60% of protein in cartilage
- makes up 85-90% of collagen in articular cartilage
- may reduce popping knees*
- may support back, jaw, and joints*
- includes glucosamine, chondroitin, and hyaluronic acid
Finding a high-quality collagen supplement in the type you need and formulated for easy absorption is easy once you know what to look for. Collagen supplements are appropriate and beneficial for adults of all ages. Hydrolyzed collagen supplements are available in the form of tablets, capsules, powder, or even tasty chewables!
Suggested Collagen Supplements
We are proud to introduce our new line of premium collagen-based products from NeoCell – the largest collagen company in the world. All of their collagen products are derived from pharmaceutical grade bovine collagen from grass fed, free range cows that are hormone and antibiotic free. Free from gluten, wheat, soy, lactose, starch, corn, yeast and artificial flavors.
Super Collagen Powder contains Super Collagen Types 1 & 3, which make up 90% of the body’s collagen supply. May support skin, hair, nail, ligament, tendon, bone, and muscle health. Add powder to water or juice and blend.
Super Collagen + C with Super Collagen Types 1 & 3, which make up 90% of the body’s collagen supply. Includes Vitamin C as an essential component to collagen absorption. May support the health of skin, hair, nails, ligaments, tendons, bones, and muscles.
Collagen Type 2 Joint Complex contains natural chicken collagen Type 2 protein with hyaluronic acid, glucosamine, and chondroitin. Take with orange juice or Vitamin C drink on an empty stomach. May support cartilage health and function.
Move Matrix Advanced Joint Hydrator from NeoCell provides scientifically advanced ingredients that work synergistically in the body to promote healthy joints. This premium formula supports joint flexibility, range of motion, and a healthy inflammatory response. Like all NeoCell products, Move Matrix is standardized to be bioactive for potent absorption and efficacy.*
Joint Burst Chews offer a tangy, juicy option for a Collagen 2 supplement! Hyaluronic acid and turmeric round out each delicious bite and offer support for connective tissues, joint fluidity, and a healthy inflammation response.*
Beauty Infusion Tangerine helps you get your collagen in a refreshing and delicious drink for radiant beauty from the inside out. Enfused with essential nutrients including 6,000 mg of NeoCell Collagen Types 1 & 3, 50 mg of hyaluronic acid, 3,000 mcg of biotin, and alpha lipoic acid and Vitamin C.
Derma Matrix Collagen Skin Complex features 6,000mg of BioActive NeoCell Collagen™ in a powder combining Collagen Types 1 & 3, Vitamin C, and Hyaluronic Acid in a technologically advanced combination created to nourish and hydrate skin. Instantly dissolves in water.
Beauty Bursts Soft Chews are an easy and delicious way to get Collagen Types 1 & 3 combined with hyaluronic acid for hydration and Vitamin C for absorption and antioxidant benefits.* Free of gluten, wheat, dairy, soy and yeast and only 4g of sugar per serving.
- Glycine http://www.ncbi.nlm.nih.gov/pubmed/20093739
- L-proline https://pubchem.ncbi.nlm.nih.gov/compound/L-proline
- Hydroxyproline http://emedicine.medscape.com/article/2087938-overview
- L-alanine https://pubchem.ncbi.nlm.nih.gov/compound/L-alanine
- Mark’s Daily Apple (Mark Sisson) – 10 Reasons to Eat More Collagen