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Myomin and Myomin Plus are all-natural Chinese herbal blends ideal for normalizing estrogen levels in both men and women. Myomin has been shown to help metabolize unhealthy estrogens and promote proper hormonal balance in the body. † Clinical case studies show that Myomin is able to reduce estradiol (estrogen) levels in as little as 10 days.1
Myomin competes with estradiol (the most active form of estrogen) at estrogen receptor sites, and can therefore be especially effective for estrogen-dominant conditions including fibroids, cysts, PMS and hormone related weight gain, among others.† It also acts by inhibiting the aromatase enzyme, stopping the conversion of androgens into estrogen.†
Additionally, Myomin can also induce more interferon in the system, which activates "natural killer cells", a major component of the immune system.† This action can be beneficial for men with enlarged prostates and for women with uterine fibroids.†
Clinical studies show that through its aromatase inhibition and estrogen blocking functions, Myomin is able to reduce estradiol and improve estrogen dominant conditions like fibroids, fibrocystic breasts, ovarian cysts, and endometriosis, among others. Read on for more about Myomin for specific conditions.
Myomin works as an estrogen blocker by competing with estradiol at the estrogen receptor sites of target cells. This stops the signaling that triggers cell division (growth) of target (estrogen sensitive) tissues.
When estrone and estradiol production is reduced or blocked, the synthesis of estriol, the good estrogen, continues. Estriol has been found to have anticarcinogenic effects. Studies show that estriol provides the benefits that estrone and estradiol do, and may also have a better safety profile.2,3
Oct 2008 - J. Iannetta, DC from ME, has a 57-year-old female patient with vaginal bleeding. A test on August 18, 2007 showed that she had a very high estradiol level for her age: 413 pg/ml. On October 2, 2008, after taking Myomin for 14 months, her estradiol level reduced significantly to 43 pg/ml.
Hyper-Aromatization of testosterone—where an enzyme called aromatase converts testosterone into estrogen—is a key contributor to estrogen dominance. Clinical studies show that Myomin works as a natural aromatase inhibitor that reduces estradiol and estrone in both men and women. Myomin prevents the conversion of testosterone into unhealthy estrogens (estradiol and estrone) making more testosterone available, and leads to the unhindered production of more beneficial estrogen (estriol) from progesterone, DHEA, and other hormones.
Dr. Jonathan Wright states that:
"Myomin is a safe and effective aromatase inhibitor that can block estradiol in both men and women."
According to Dr. Chi, the maker of Myomin:
"The importance of aromatase inhibitors in the treatment of hormone-related conditions has gained momentum in the past few years. One of the advantages of Myomin is that it can be used by men as well as pre- and postmenopausal women."
Estradiol is the most active form of estrogen.
Dr. Chi says, "estrogen dictates important mechanisms such as protein production and cell division, and is vital to growth processes not just during puberty, but in adult life. However, its role in signaling cells to divide and multiply can trigger and promote abnormal growth of estrogen-responsive tissues. Minimizing estrogen, therefore, is a clear goal for estrogen-responsive conditions."
Case reports illustrate that Myomin not only reduces estradiol, it also increases the 2/16 estrogen metabolite ratio. According to Dr. Jonathan Wright, the ideal 2/16 ratio should be over 2. If the ratio falls below 2, risk for prostate, testicular, ovarian, breast and uterine cancer increases. Myomin effectively increases the 2/16 ratio.
The primary role of estrogen for women is to maintain the growth and function of the uterus so that the sex organs can become adult sized, and prepares the uterine lining to accept an egg. Good estrogens have a positive affect on skeletal growth, skin, fat and protein deposition, and electrolyte balance for both women and men.
Myomin Plus has the same primary function as Myomin, but with less gastrointestinal side effects. Recommended for those (about 2%) who experience bloating, upset stomach, or other digestive-related symptoms when taking Myomin. Notopterygium incisium has been added to counteract those gastrointestinal side effects. See the Supplement Facts tab on either product page for the full list of ingredients.
Fibroid tumors are usually benign (non-cancerous) tumors occurring in the uterus. Medically, fibroids are also referred to as myomas or leiomyomas, and are considered to be a woman's fibrosis condition that is usually associated with estrogen dominance.
Women who experience uterine fibroid symptoms may suffer from pelvic pain, abnormal menstruation, and a variety of other conditions. Pregnancy may be complicated, resulting in miscarriage, premature birth, and other difficulties.
Myomin can be particularly effective for fibroid tumors because it helps to metabolize estradiol, the most active form of estrogen, which essentially "spurs" tumors to grow. When estradiol is properly metabolized, it lessens the tendency for estrogen to promote tumor growth.
Case studies from many different health care providers report that Myomin has shown to be particularly effective for helping to reduce fibroid tumors. For example:
Dr. Schueler of Virginia reports about a 40-year-old female patient with a 10cm fibroid. After taking Myomin for 6 months, her tumor reduced greatly in size.
Polycystic Ovarian Syndrome (PCOS) may be caused by an imbalance of hormones, including excess testosterone, estrogen dominance, insulin resistance, or a combination of these. Likewise, endometriosis is thought to be caused by hormonal imbalances, including estrogen dominance. Myomin can help with both conditions, as it promotes proper hormone balance within the body.
A clinical study was conducted on 255 patients with ovarian cysts and endometriosis. After 5 months, Myomin was effective in 147 patients (57.6%), while some improvement was observed in 87 patients (34.1%). No effect was observed in only 21 patients.
Managing PCOS involves inducing ovulation, making the menstrual cycle normal and reducing associated symptoms.
In many cases, supplementation with progesterone is also recommended.
Myomin can be helpful for managing fibrocystic breasts, often associated with estrogen dominance.
A study from Chang Hai Hospital involved 75 cases of fibrocystic breasts (70 women ages 18 to 52 years old and 5 men ages 62 to 64 years old). Sixty-five percent of the women were under 35 years old. 25 cases were in the control group while 50 cases were in the Myomin group.
Results of the study revealed that, in 14 cases, the fibrocystic breast completely cleared after 1 month of taking myomin while, in 16 cases, the fibrocystic breast reduced 50% in size. Among the five men in the study, the cysts cleared completely in 3 cases.
Myomin on Fibrocystic Breast in Men and Women
Number of cases
Overall the effective rate of Myomin is more than 60% compared to the control group's 12% rate. In the Myomin group, in 48 out of 50 cases, associated pain cleared or tremendously reduced (p value <0.05) while in the control group, pain reduced in only 12 out of 25 cases.
Reducing estrogen can also help reduce abdominal fat, which is relatively common among the middle-aged.
Excess abdominal fat has been associated with decreased testosterone levels and increased estradiol (estrogen) levels. As fat accumulates in the abdomen, aromatase activity increases, causing more testosterone to be converted into estradiol.4 This leads to a troublesome cycle, that unless addressed, can cause serious weight loss frustration.
In many cases, exercise and a healthy diet are not enough to reduce belly fat. Often, hormone imbalances must be addressed as well for successful weight loss to occur.
Including Myomin in your weight loss protocol will block aromatase, effectively preventing testosterone from being converted into estradiol. This leads to more muscle mass and the loss of abdominal weight.5
Dr. Jonathan Wright points out that excess aromatization of testosterone into estrogen is usually accompanied by insulin resistance; hence, those who have Type II diabetes and/or are overweight (especially in the abdomen) will benefit from Myomin to reduce their estrogen level, and thus reduce belly fat and help manage insulin resistance.
While there may be conflicting reports regarding the role of estradiol in the development of prostate cancer, there is mounting evidence demonstrating estradiol's effect on prostate cancer.
What we do know is that estrogen does promote the development of Benign Prostatic Hyperplasia (BPH). Estrogen stimulates the cells in the tissue surrounding the prostate, leading to urinary symptoms associated with prostate disease.8 Furthermore, in one study, BPH patients were found to have greater estradiol levels than those without BPH.9
While some studies show that there is no relationship between serum estradiol and prostate cancer, this may be explained by the fact that prostate cells produce their own estradiol locally. Estradiol may be high around the prostate, but it may not show up in a blood test. Local synthesis of estrogen has been thought to play a role in prostate cancer development.10
Dr. Jonathan Wright states in his article that prostate cancer development and andropause (male menopause, wherein testosterone levels decrease and estrogen levels increase) are associated. This may be because when men reach andropause, the ratio of estrogens to androgens can reach up to 40%. He recommends that men avoid regular soy consumption as this can potentially increase estrogen.
Myomin can be helpful to restore normal estrogen and testosterone levels in men.
Although postmenopausal women have significantly reduced estrogen production, their risk of certain estrogen-related conditions still exists. Factors that affect their risk include long-term hormone stimulation, overexpression of aromatase, xenoestrogens, low progesterone, and belly fat.
Those who have been on HRT for a long time are exposed to long-term hormone stimulation. According to a study, among women with fibrocystic breasts for over 20 years who have been exposed to hormone stimulation, 17% developed breast cancer.
Incorporating Myomin into a postmenopausal supplement protocol will help to ensure healthy estrogen metabolism and hormone balance.
We learned from the 2002 Women's Health Initiative Study that synthetic hormones can increase the risk for breast cancer, heart disease, stroke and blood clots. Chi Enterprises, the manufacturer of Myomin states:
"Those who are taking hormones, bioidentical or synthetic, should also take Myomin in order to prevent the conversion of testosterone and other hormones into estradiol and estrone, the harmful estrogens."
According to a 2009 study, HRT users (with or without progesterone) have a 44% increased risk for ovarian cancer. Those using an estrogen patch have a 13% higher ovarian cancer risk. Those who use intravaginal estrogen have a 23% increased ovarian cancer risk.11
The risk may not only be from estrogen but from other hormones as well. Various hormones including progesterone, testosterone, and DHEA have some kind of impact on the three forms of estrogen: estrone, estradiol and estriol.
By blocking the aromatase enzyme, Myomin is able to stop or reduce the synthesis of estrone and estradiol from progesterone, DHEA, androstenedione, and testosterone. Furthermore, Myomin may also loosely inhibit the synthesis of estrone into 16OH-estrone, as discussed above.
Achieve a Healthy Estrogen Quotient with Myomin - An article in the Journal of the American Naturopathic Medical Association (JAMNA) published July 2012.
The Townsend Newsletter - Myomin, Natural Aromatase Inhibitor for estrogen related conditions.
Hormonal Balance - for more information about balancing hormones.
Estrogen Dominance - For further information about hormones, estrogen dominance, and environmental estrogens.
Fibroid Tumors - to learn about fibroid tumors.
In addition to Myomin, people with estrogen dominant conditions may also consider using these complementary products.
DIM promotes beneficial estrogen metabolism and healthy hormonal balance 1,2,3. This optimizes the ratio of estrogen metabolites that is crucial for breast3, uterine4, cervical5, and prostate6 health. Women and men also use DIM as an integral part of successful weight management programs. See note below for choosing Myomin and/or DIM.
Calcium D-Glucarate is a relatively common nutrient found in many fruits and vegetables. Many believe that this nutrient aids the body in the elimination of many harmful substances and helps to lower abnormally high levels of steroid hormones including estrogen, testosterone, and progesterone. Both of these effects may help to protect against the development of certain tumors.†
Natural progesterone is used to maintain a normal level of progesterone and a balanced ratio of estrogen to progesterone. Natural USP progesterone is biologically identical to the hormone women produce, and offers an alternative to taking synthetic hormones. Additionally, it protects against the undesirable side effects of excess estrogen.
Myomin is a formula of Chinese herbs that has been shown to metabolize excess unhealthy estrogen and acts as an aromatase inhibitor. Hospital research has shown that Myomin helps to reduce both the number and size of fibroids, fibrocystic breast cysts, and ovarian cysts. This formula also contains herbs that are touted by the PDR for Nutritional Supplements as having anti-tumor properties.
DIM is derived from a blend of cruciferous vegetables including broccoli, cauliflower, and Brussels sprouts. Research shows it helps can help metabolize unhealthy circulating estrogens (estrone, estradiol) into the good form (estriol) for both women and men. Like Myomin, DIM is also considered an aromatase inhibitor. DIM is generally recommended for those who are menstruating (twenties and early thirties) or premenopausal (mid-thirties on) with higher estrogen levels.
Myomin is often suggested for those who are menopausal to post-menopausal because it is not as strong of a metabolizer as DIM; although, Myomin can be used by premenopausal women, as well.
Myomin does have actions that differ from DIM; therefore, some women choose to take them together for a more aggressive approach. For example, Myomin contains an herb that can help support over-worked adrenal glands. It also contains curcumin; according to the Physicians Desk Reference (PDR) for Nutritional Supplements, "curcumin and other curcuminoids have been found to have antioxidant, anti-inflammatory, antiviral, antifungal, and immune-modulating effects".
Having an initial hormone test can help determine how much estrogen metabolizing one may need and will establish baseline results that can be used as a comparison for future tests. Periodic hormone testing can allow for any necessary dosage adjustments regarding the intake of DIM and/or Myomin.
Balance is the key to hormonal health. Therefore, it is a good idea not to exceed the recommended doses on the product labels and watch out for signs of over-metabolizing your estrogen. An indication that estrogen has been over-metabolized would be hot flashes that did not occur prior to adding DIM and/or Myomin to your regimen.
It is very important to understand that what may be true for one person is not necessarily true for another. The journey of hormonal changes is an individual one. What this also implies is that the usage of products for one individual can be quite different from that of another.
Note: Those taking DIM and/or Myomin for estrogen dominance that do not experience a reduction in symptoms or unhealthy estrogen levels may want to consider adding Calcium D-Glucarate to their regimen. This dietary supplement helps make sure that used hormones are eliminated from the body rather than reabsorbed into the bloodstream where they can be deposited in tissues and cells.
The Townsend Newsletter – Myomin, Natural Aromatase Inhibitor for Estrogen-Related Conditions.
"A human study involved 60 postmenopausal women with cysts. Postmenopausal women were studied because their estradiol levels are more stable than those of premenopausal women. Initially, the average estradiol level was 74.58 pg/ml. After only 10 days on Myomin, their average estradiol level reduced to 38.84 pg/ml. The fibroids, cysts, and the associated pain gradually reduced."
"Another study was conducted on both pre- and postmenopausal women with ovarian cysts. In one study from the Chang Hai Hospital in Shanghai, China, 85 female patients with ovarian cysts were involved, with ages ranging from 27 to 64 years old (more than 50% of them between 34 and 45 years old). Out of the 85, 40 cases were related to endometriosis (hydatidiform cyst), 44 cases were simple ovarian cysts…after 1 to 3 courses of the herbal formula, the cysts and symptoms of 15 patients completely cleared with no recurrence 3 months after the study. In 34 patients, the size of the cyst reduced by 50% and some of the associated symptoms were relieved."
One study involved men and women with fibrocystic breasts. In three of the five men in the study, their cysts cleared completely. In that same study, 65% of the women were under 35 years old, demonstrating that this herbal formula is not only limited to postmenopausal women.
R. Santoro, ND from NY has a 75 y/o/m patient who has tried to reduce his estradiol and increase his testosterone for a long time to no avail. Only Myomin has reduced his estradiol level and increased his testosterone by 100 points after a year.
B. Sanborn, DC from MI has a 16 y/o/m patient with gynecomastia. His estradiol and DHT levels were both high. He has tried 8 different supplements, including DIM and indole-3-carbinol (I3C); however, they didn't have much effect on him. After taking Myomin and Prosta Chi for two months, his estradiol level reduced from 300 to 70 and his DHT level reduced from 1,100 to 250 (this means he is not converting testosterone into DHT). His gynecomastia also improved.
V. Vidov, MD from NY reports on a 40-year-old female who had a fibroid cyst in the breast the size of an egg. After only 3 months of taking Myomin, the cyst disappeared.
A. Schueler, DC from VA reports on a 40-year-old female who had a 10cm fibroid cyst. After taking Myomin for 6 months, her fibroid cyst has greatly reduced in size.
M. McCain, ND from AR, quotes: "Myomin has proven exceptional in reducing hard to dissolve fibroid tumors and liver and kidney cysts. We have many remarkable testimonials."
J. Stickel, DC from IA reports on a patient with uterine fibroids and colon polyps. After taking Myomin for only 3 months, her uterine fibroids and polyps had completely disappeared.
S. Young, ND from CO reports on a 38-year-old female patient with a colloid cyst on her thyroid. MD was giving RX to shut down her thyroid "and see what would happen." She tried Myomin instead and the cyst melted away in 3 weeks.
K. Hajduk, DC from CA reports on a 50-year-old male whose PSA level was 7.9. He recommended that the patient take Myomin and Revivin and use the MIT once a day. After 4 months, the patient's PSA dropped to 2.
T.C., a 58-year-old male from CA has prostatitis and has take Saw Palmetto for years. In early 2003, Saw Palmetto no longer worked for him and so he switched to Myomin with excellent results.
Y. Dikansky, DDS, NMD from NY reports on a 38-year-old female who had an ovarian cyst for 8 years. The cyst was 3.7x6x2. After taking Myomin for 3 months, the cyst disappeared.
W. Stimack, NMD from ID reports on a 29-year-old female patient with 12 fibroids that made her look like she was 8 months pregnant. She used Myomin for 5 months and now it is all clear.
J. Wright, MD from WA has a male patient who took Myomin for 4 months. His estrogen level has sharply dropped.
R. Bernhoft, R. Bernhoft, MD from CA has a 50-year-old male patient with elevated estradiol and abnormal PSA levels. He took Myomin and Prosta Chi for 3 months and his estradiol returned to normal. His abnormal PSA level has reduced to 1.6 after a year.
D. Brookes, RN from VT reports on a patient who had a uterine tumor and breast cyst. She then used Myomin for 2 months and had marked improvement. Then she added Angiostop and Revivin. Six months later, her uterine tumor has reduced significantly and breast cyst has almost cleared.
L. P., 38-year-old female from NY had 5 fibroids that were surgically removed. Then the fibroids recurred with heavy bleeding. She used Myomin and Angiostop. After two months, her periods were not as heavy and the fibroids have reduced.
Feb 2010 – D. Caron, DC from SD, has a 52 y/o/m patient whose testosterone level increased from 280 to 460 after 6 months on Myomin.
Dec 2009 – I. Mena, DO from CA has a 40 y/o/f patient with multiple fibroids (even one 3.5 cm in diameter). After 4-5 months on Myomin, an ultrasound revealed that the fibroids completely cleared.
Oct 2009 – A. Heyer, PhD from NY has a 35 y/o/f patient who has had vaginal polyps (about 1 ½ cm in diameter) for at least a year. Intercourse often causes bleeding. After taking Myomin, Revivin, and Vein Lite, her polyps have reduced in size and she feels better.
Dec 2009 – H. Khudatyan, MD from CA, reports that he has successful results using Myomin on breast cysts, uterine fibroids, ovarian cysts and vaginal discharge.
Aug 2009 – D.L., 61 y/o/f from FL, has had a benign breast mass for 10 years. After taking Myomin for a year, the mass cleared.
Sep 2009 – K.H., 60 y/o/m from CA, has belly fat and somewhat large breasts. Both reduced by about 50-60% by using Myomin for 6 months.
Sep 2009 – S. Malkhasian, ND from CA,has a 48 y/o/f patient with multiple cysts in both breasts. After taking Myomin and Angiostop for 6 months, the cysts in one breast completely cleared while only one small cyst remained in the other breast.
Aug 2009 – P.L., 56 y/o/f from FL, had a 6 x 4 x 4 mm nodule in the breast. It reduced in size after a year on the program. Her doctors stated that there has been improvement in overall nodularity of the patient's breast, especially on the right side when compared to July 2008. Three years previous, she had 5 colon polyps. Her colon is doing well now. Also, her TSH level is now 0.149. She was able to reduce her Armour Thyroid dose from 90 mg to 60 mg with Pro-Metabolic. Her HgA1c level also reduced to 4.4.
Oct 2009 – M.C., 60 y/o/f from NY took Myomin for at least 2 months and reduced 2 dress sizes and had more energy.
Oct 2009 – C.T., 62 y/o/f from NY, had hot flashes for 10 years. She has tried everything, including black cohosh and wild yam extract, but hasn't been successful. Two years ago, she started taking Myomin and her hot flashes have cleared.
Oct 2008 - J. Iannetta, DC from ME, has a 57-year-old female patient who had vaginal bleeding. A test on August 18, 2007 showed that she had very high estradiol level for her age: 413 pg/ml. On October 2, 2008, after taking Myomin for 14 months, her estradiol level has reduced significantly to 43 pg/ml.
Sep 2008 - E. Schlabach, DC from OH, reports that according to many patient urine lab tests, Myomin at 9 capsules per day not only can reduce estradiol but also can increase the 2/16 estrogen metabolite ratio quickly. Readings ranged from 1.0-0.6 before taking Myomin. After two weeks of taking Myomin the ratio increased to over 2.0 to 6.0.
Oct 2008 - J. Blair, ND from NJ, has a 48-year-old female patient who has had dense breasts since she started having a period over 30 years ago. A mammogram was not adequate to test her breasts for lumps; she always needed an ultrasound for that. After taking Myomin for approximately one year, she reports that for the first time in her life, a mammogram showed a clear picture, no more denseness at all. Her breast pain was also eliminated and her period became regular.
Sep 2009 – D. Ring, RPh from Australia, has a 61 y/o/m patient with BPH. After taking Myomin and Angiostop for a year, the size of his prostate reduced from 285cc to 225cc and at last report, was down to 60cc.
July 2, 2009 – L. Fitzwilliams, DC from OR, has a male patient with a PSA level of 10.6 and was scheduled for prostate surgery. She recommended Prosta Chi, Myomin and Calcium D-Glucarate for 3 months. His PSA reduced to 3.4 and his estradiol level reduced as well. He may not need surgery after all.
Aug 2009 – K.G., DC from FL, had elevated PSA which reduced to within normal range on the prostate program. So he stopped the regimen. Then recently in February 2009, his PSA spiked up again to 8. So he started back on the program again. After 6 months, his PSA reduced to 4.93.
Oct 2009 – J. Iannetta, DC from ME, has a male prostate cancer patient with a PSA level of 5.4. After about 5 months on Angiostop, Revivin, Myomin, Reishi Spore Extract and Asparagus Extract, his PSA level reduced to 3.8.
Aug 2008 - B. Sanborn, DC from MI, reported on a 16-year-old male patient with gynecomastia. His estradiol and DHT levels were both high. After taking Myomin and Prosta Chi for two months, his estradiol level reduced from 300 to 70 and his DHT level reduced from 1,100 to 250. His gynecomastia also improved.
Capsules per Container: 120 Capsules, 500 mg.
Serving Size: Two (2) Vegetarian Capsules
Amount per Serving, 1000 mg contains:
*Daily Value not established for these ingredients.
No preservatives, no sodium, no artificial colors, no yeast, no animal product.
Keep bottle tightly closed. Store in a cool, dry place. Keep out of reach of children.
Myomin and Myomin Plus is manufactured by Chi's Enterprise, Inc. It undergoes strict quality control to ensure a clean and effective product. All herbs used in Chi's formulas are rigorously screened for heavy metals by the USDA and FDA.
Founded in 1986 by Dr. Tsu-Tsair Chi, Chi's Enterprise is a well-respected leader in Herbal Alternative Medicine, offering sound, research-based supplements to people worldwide. Dr. Chi received medical training in China and earned his PhD in Biochemistry from Rutgers University in 1978. He is also a Board Certified Naturopathic Physician. Chi's product formulations are designed using both eastern and western healthcare methodologies to help you achieve optimum health naturally.
As a dietary supplement, take 2 to 3 capsules per use, 2 to 3 times a day after meals, or as directed by your healthcare practitioner.
† These statements have not been evaluated by the U.S. Food and Drug Administration (FDA) or EnergeticNutrition.com. This product is not intended to diagnose, treat, cure or prevent any disease. The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging. You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. You should consult with a health care professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem, or are pregnant. When you receive an item, carefully read all labels, warnings, and directions before use. Actual product packaging and materials may contain more and/or different information than shown on this website.