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Melatonin - Peppermint Sublingual
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Melatonin - Peppermint Sublingual

Helps Promote Sleep

from Source Naturals
$12.25
Retail $17.50
 you save 30%
Size: 200 Tablets - 1 mg
Item: 5630
Weight: 0.19 lbs
Points: 61
Melatonin is a neurohormone that is naturally produced in humans by the pineal gland. It is a favorite of travelers, as it governs the body's circadian rhythms, helping to regulate our sleep cycles. Melatonin is also a potent antioxidant. This sublingual form is absorbed directly into the bloodstream, via the blood vessels under the tongue and in the cheeks, bypassing the liver and allowing for quick entry into the system.

  • Description
  • Supplement Facts & Suggested Use
  • Reviews

Melatonin - Peppermint Sublingual for Occasional Sleeplessness

  • HW-vegetarian
  • MG-gluten-free
  • ND-dairy-free
  • OS-soy-free
  • PY-yeast-free
  • QH-non-gmo

Melatonin is a neurohormone that is naturally produced in humans by the pineal gland, a cone shaped structure in the brain. It is a favorite of travelers, as it governs the body's circadian rhythms, helping to regulate our sleep cycles. Melatonin is also a potent antioxidant.

This sublingual form is absorbed directly into the bloodstream, via the blood vessels under the tongue and in the cheeks, bypassing the liver and allowing for quick entry into the system.


How Melatonin Works

Melatonin is secreted by the pineal gland in the brain that helps regulate other hormones and maintains the body's circadian rhythm, as mentioned above. The circadian rhythm is an internal 24-hour time-keeping system that plays a critical role in determining when we fall asleep and when we wake up. Darkness stimulates the production of melatonin while light suppresses its activity. Exposure to excessive light in the evening or too little light during the day can disrupt the body’s normal melatonin cycles. For example, jet lag, shift work, and poor vision can disrupt melatonin cycles. In addition, some experts claim that exposure to low-frequency electromagnetic fields (common in household appliances), and exposure to close proximity electronic devices (smart phones, tablets) may disrupt normal cycles and production of melatonin.†

Melatonin also helps control the timing and release of female reproductive hormones. It helps determine when menstruation begins, the frequency and duration of menstrual cycles, and when menstruation ends (menopause).

Many researchers also believe that melatonin levels are related to the aging process. For example, young children have the highest levels of nighttime melatonin. Researchers believe these levels diminish as we age. In fact, the decline in melatonin may explain why many older adults have disrupted sleep patterns and tend to go to bed and wake up earlier than when they were younger. However, emerging research calls this theory into question.

In addition to its hormonal and sleep actions, melatonin has been shown to have strong antioxidant effects. Preliminary evidence suggests that it may also help strengthen the immune system.†


Melatonin and Occasional Sleeplessness

Although results are still controversial, studies suggest that melatonin supplements help induce sleep in people with disrupted circadian rhythms, jet lag, poor vision, and those with low melatonin levels. In fact, a few studies suggest that when taken for short periods of time (days to weeks) melatonin is significantly more effective than a placebo, or “dummy pill,” in decreasing the amount of time required to fall asleep, increasing the number of sleeping hours, and boosting daytime alertness.†

In addition, at least one study suggests that melatonin may improve the quality of life in people who suffer from poor sleep cycles. Although research suggests that melatonin may be modestly effective for regulating sleep, few studies have investigated whether melatonin supplements are safe and effective for long term use.


Possible Interactions

If you are currently being treated with any of the following medications, you should not use melatonin without first discussing it with your doctor.

  • Antidepressant Medications
  • Antipsychotic Medications
  • Benzodiazepines
  • Blood Pressure Medications or Beta-Blockers
  • Blood-Thinning Medications, Anticoagulants
  • Interleukin-2
  • Nonsteroidal Anti-inflammatory Drugs (NSAIDs)
  • Steroids and Immunosuppressant Medications

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References

  • Arendt J. Melatonin, circadian rhythms and sleep. New Engl J Med ; 2000;343(15):1114-1116.

  • Attele AS, Xie JT, Yuan CS. Treatment of insomnia: an alternative approach. Altern Med Rev . 2000;5(3):249-259.

  • Baumgaertel A. Alternative and controversial treatments for attention-deficit/hyperactivity disorder. Pediatr Clin N Am. 1999;46(5):977-992.

  • Bazil CW, Short D, Crispin D, Zheng W. Patients with intractable epilepsy have low melatonin, which increases following seizures. Neurology. 2000;55(11):1746-1748.

  • Bekaroglu M, Aslan Y, Gedik Y. Relationships between serum free fatty acids and zinc, and attention deficit hyperactivity disorder: a research note. J Child Psychol Psychiatry. 1996;37(2):225-227.

  • Ben-Nathan D, Maestroni GJ, Lustig S, Conti A. Protective effects of melatonin in mice infected with encephalitis viruses. Arch Virol. 1995;140(2):223-230.

  • Bonilla E, Valero-Fuenmayor N, Pons H, Chacin-Bonilla L. Melatonin protects mice infected with Venezuelan equine encephalomyelitis virus. Cell Mol Life Sci. 1997;53(5):430-434.

  • Brzezinski A. "Melatonin replacement therapy" for postmenopausal women: is it justified? Menopause. 1998;5:60-64.

  • Bylesjo I, Forsgren L, Wetterberg L. Melatonin and epileptic seizures in patients with acute intermittent porphyria. Epileptic Disord. 2000;2(4):203-208.

  • Carman JS, Post RM, Buswell R, Goodwin FK. Negative effects of melatonin on depression. Am J Psychiatry. 1976;133:1181-1186.

  • Cauffield JS, Forbes HJ. Dietary supplements used in the treatment of depression, anxiety, and sleep disorders. Lippincotts Prim Care Pract. 1999; 3(3):290-304.

  • Chase JE, Gidal BE. Melatonin: Therapeutic use in sleep disorders. Ann Pharmacother. 1997;31:1218-1225.

  • Cornelissen G, Halberg F, Burioka N, Perfetto F, Tarquini R, Bakken EE. Do plasma melatonin concentrations decline with age? Am J Med. 2000;109(4):343-345.

  • Dagan Y, Zisapel N, Nof D, et al. Rapid reversal of tolerance to benzodiazepine hypnotics by treatment with oral melatonin: a case report. Eur Neuropsychopharmacol. 1997;7(2):157-160.

  • Dreher F, Denig N, Gabard B, Schwindt DA, Maibach HI. Effect of topical antioxidants on UV-induced erythema formation when administered after exposure. Dermatology. 1999;198(1):52-55.

  • Dreher F, Gabard B, Schwindt DA, Maibach HI. Topical melatonin in combination with vitamins E and C protects skin from ultraviolet-induced erythema: a human study in vivo. Br J Dermatol. 1998;139(2):332-339.

  • Fauteck J, Schmidt H, Lerchl A, Kurlemann G, Wittkowski W. Melatonin in epilepsy: first results of replacement therapy and first clinical results. Biol Signals Recept. 1999;8(1-2):105-110.

  • Ferini-Strambi L, Zucconi M, Biella G, et al. Effect of melatonin on sleep microstructure: preliminary results in healthy subjects. Sleep. 1993;16(8):744-747.

  • Forsling ML, Wheeler MJ, Williams AJ. The effect of melatonin administration on pituitary hormone secretion in man. Clin Endocrinol (Oxf). 1999;51(5):637-642.

  • Garfinkel D, Laundon M, Nof D, Zisapel N. Improvement in sleep quality in elderly people by controlled-release melatonin (see comments). Lancet. 1995;346(8974):541-544.

  • Garfinkel D, Zisapel N, Wainstein J, Laudon M. Facilitation of benzodiazepine discontinuation by melatonin: a new clinical approach. Arch Intern Med. 1999;159(8):2456-2460.

  • Haimov I, Laudon I, Zisapel N, Souroujon M, Nof D, Shiltner A, et al. Sleep disorders and melatonin rhythms in elderly people. BMJ. 1994(9120);309:167.

  • Herxheimer A, Petrie KJ. Melatonin for preventing and treating jet lag. Cocharane Database Syst Rev. 2001;(1):CD001520.

  • Kennedy SH. Melatonin disturbances in anorexia nervosa and bulimia nervosa. Int J Eating Disord. 1994;16:257-265.

  • Kirkwood CK. Management of insomnia. J Am Pharm Assoc. 1999;39(1):688-696.

  • Lagneux C, Joyeux M, Demenge P, Ribuot C, Godin-Ribuot D. Protective effects of melatonin against ischemia-reperfusion injury in the isolated rat heart. Life Sciences. 2000;66(6):503-509.

  • Lewy AJ, Bauer VK, Cutler NL, Sack RL. Melatonin treatment of winter depression: a pilot study. Psych Res. 1998;77(1):57-61.

  • Melatonin Overview. University of Maryland Medical Center.

  • Murphy P, Myers B, Badia P. NSAIDs suppress human melatonin levels. Am J Nat Med. 1997; iv: 25.

  • Nagtagaal JE, Laurant MW, Kerkhof GA, Smits MG, van der Meer YG, Coenen AM. Effects of melatonin on the quality of life in patients with delayed sleep phase syndrome. J Psychosom Res. 2000;48(1):45-50.

  • Partonen T. Short note: melatonin-dependent infertility. Med Hypotheses. 1999;52(5):487-488.

Supplement Facts - Melatonin Peppermint Sublingual

Capsules per Container: 200 Peppermint Sublingual lozenges, 1 mg
Serving Size: One (1) Lozenge
Servings per Container: 200

Supplement Facts for 1 mg Peppermint Sublingual
Serving Size: 1 tablet
Melatonin, 1 mg (†)

† Daily Value not established.

Other Ingredients: sorbitol, mannitol, natural peppermint flavor, stearic acid & magnesium stearate.

Suggested Use: 1 lozenge at bedtime. Do not take more than 5 tablets daily unless recommended by your physician. Place lozenge under the tongue and allow to dissolve slowly, altering the position of the tablet to avoid prolonged contact with the same area.

Warning: USE ONLY AT BEDTIME. For adult use only. Not for use by children, teenagers, or women who are pregnant, may become pregnant, or breastfeeding. If you are under medical supervision, or have an autoimmune disease, diabetes, a depressive disorder, a thyroid condition, epilepsy, leukemia, or a lymphoproliferative disorder, or are taking MAO inhibitor drugs or corticosteroids such as hydrocortisone or prednisone, consult with your physician before taking this product.

STORE IN A COOL, DRY PLACE.

Do not use if either tamper-evident seal is broken or missing. Keep out of the reach of children.

Manufactured by Source Naturals.

† These statements have not been evaluated by the U.S. Food and Drug Administration (FDA) or EnergeticNutrition.com. This product is not intended to diagnose, treat, cure or prevent any disease. The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging. You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. You should consult with a health care professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem, or are pregnant. When you receive an item, carefully read all labels, warnings, and directions before use. Actual product packaging and materials may contain more and/or different information than shown on this website.




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